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KMID : 1130320140570030110
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Korean Journal of Pediatrics
2014 Volume.57 No. 3 p.110 ~ p.116
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Clinical utilization of cord blood over human health: experience of stem cell transplantation and cell therapy using cord blood in Korea
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Lee Young-Ho
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Abstract
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Cord blood (CB) has been used as an important and ethical source for hematopoietic stem cell transplantation
(SCT) as well as cell therapy by manufacturing mesenchymal stem cell, induced pleuripotential
stem cell or just isolating mononuclear cell from CB. Recently, the application of cell-based therapy
using CB has expanded its clinical utility, particularly, by using autologous CB in children with refractory
diseases. For these purposes, CB has been stored worldwide since mid-1990. In this review, I would like
to briefly present the historical development of clinical uses of CB in the fields of SCT and cell therapy,
particularly to review the experiences in Korea. Furthermore, I would touch the recent banking status of
CB.
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KEYWORD
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Cord blood, Transplantation, Cell therapy
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